PARSING UNKNOWNS

A Game of Unknowns.

Tsivgoulis et al previously reported that acute ischemic stroke (AIS) patients with large artery atherosclerosis (LAA) who took statins before stroke onset had fewer recurrent strokes and better functional outcomes than statin-naive patients. In this issue of ATVB, the same group reports that AIS patients with LAA taking statins before stroke onset had a significant, dose-dependent reduction in...

Knowns and Unknowns

The current work reviews literature on the nature of stalking. Despite its nebulous nature and differing legal and clinical definitions of stalking, researchers and practitioners are referring to the same phenomenon. Stalking is chronic, consisting of a number of nuisance behaviors that appear consistent over countries and samples. Different categorizations of stalkers and their victims exist, ...

The Importance of Unknowns

Xenotransplantation: assessing the unknowns.

Unmeasured anions: the unknown unknowns

Evidence is emerging that elevated concentrations of the intermediates of the citric acid cycle may contribute to unmeasured anions in critical illness. Both the anion gap and the strong ion gap are used as scanning tools for recognition of these anions. The mechanisms underlying these elevations and their significance require further clarification.